Periostat

Doxycycline Injection



(dox i sye' kleen)

Doxy 100®
Doxy 200®

Doxycycline injection is used to treat or prevent bacterial infections, including pneumonia and other respiratory tract infections. It is also used to treat certain skin, genital, intestine, and urinary system infections. Doxycycline injection may be used to treat or prevent anthrax (a serious infection that may be spread on purpose as part of a bioterror attack) in people who may have been exposed to anthrax in the air. Doxycycline injection is in a class of medications called tetracycline antibiotics. It works by killing bacteria that cause infections.
Antibiotics such as doxycycline injection will not work for colds, flu, or other viral infections. Taking or using antibiotics when they are not needed increases your risk of getting an infection later that resists antibiotic treatment.

Doxycycline injection comes as a powder to be mixed with liquid to be injected intravenously (into a vein). It is usually given every 12 or 24 hours over a period of 1 to 4 hours. The length of your treatment depends on the type of infection you have and how your body responds to the medication.
You may receive doxycycline injection in a hospital or you may administer the medication at home. If you will be receiving doxycycline injection at home, your healthcare provider will show you how to use the medication. Be sure that you understand these directions, and ask your healthcare provider if you have any questions.
You should begin to feel better during the first few days of treatment with doxycycline injection. If your symptoms do not improve or get worse, call your doctor. If you still have symptoms of infection after you finish doxycycline injection, tell your doctor.
Use doxycycline injection until you finish the prescription, even if you feel better. If you stop using doxycycline injection too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics.

Before taking doxycycline,

tell your doctor and pharmacist if you are allergic to doxycycline, minocycline, tetracycline, demeclocycline, any other medications, sulfites, or any of the ingredients in doxycycline capsules, extended-release capsules, tablets, extended-release tablets, or suspension. Ask your pharmacist for a list of the ingredients.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, and nutritional supplements you are taking or plan to take. Be sure to mention any of the following: acitretin (Soriatane); anticoagulants ('blood thinners') such as warfarin (Coumadin, Jantoven); barbiturates such as butabarbital (Butisol), phenobarbital, and secobarbital (Seconal); bismuth subsalicylate; carbamazepine (Epitol, Tegretol, others); isotretinoin (Absorica, Amnesteem, Clavaris, Myorisan, Zenatane); penicillin; phenytoin (Dilantin, Phenytek); and proton pump inhibitors such as dexlansoprazole (Dexilant), esomeprazole (Nexium, in Vimovo), lansoprazole (Prevacid, in Prevpac), omeprazole (Prilosec, in Yosprala, Zegerid), pantoprazole (Protonix), and rabeprazole (Aciphex). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

be aware that antacids containing magnesium, aluminum, or calcium, calcium supplements, iron products, and laxatives containing magnesium interfere with doxycycline, making it less effective. Take doxycycline 2 hours before or 6 hours after taking antacids, calcium supplements, and laxatives containing magnesium. Take doxycycline 2 hours before or 4 hours after iron preparations and vitamin products that contain iron.

tell your doctor if you have or have ever had lupus (condition in which the immune system attacks many tissues and organs including the skin, joints, blood, and kidneys), intracranial hypertension (pseudotumor cerebri; high pressure in the skull that may cause headaches, blurry or double vision, vision loss, and other symptoms), a yeast infection in your mouth or vagina, surgery on your stomach, asthma, or kidney or liver disease.

you should know that doxycycline may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, or injections). Talk to your doctor about using another form of birth control.

tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. If you become pregnant while taking doxycycline, call your doctor immediately. Doxycycline can harm the fetus.

plan to avoid unnecessary or prolonged exposure to sunlight and to wear protective clothing, sunglasses, and sunscreen. Doxycycline may make your skin sensitive to sunlight. Tell your doctor right away if you get a sunburn.

you should know that when you are receiving doxycycline for prevention of malaria, you should also use protective measures such as effective insect repellent, mosquito nets, clothing covering the whole body, and staying in well-screened areas, especially from early nighttime until dawn. Taking doxycycline does not give you full protection against malaria.

you should know that when doxycycline is used during pregnancy or in babies or children up to 8 years of age, it can cause the teeth to become permanently stained. Doxycycline should not be used in children under 8 years of age except for inhalational anthrax, Rocky Mountain spotted fever, or if your doctor decides it is needed.

Unless your doctor tells you otherwise, continue your normal diet.

Take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.

Doxycycline may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:



nausea

vomiting

diarrhea

loss of appetite

itching of the rectum or vagina

sore or irritated throat

swollen tongue

dry mouth

anxiety

back pain

changes in color of skin, scars, nails, eyes, or mouth

Some side effects can be serious. If you experience any of these symptoms, call your doctor immediately:



headache

blurred vision, seeing double, or loss of vision

rash that may occur with fever or swollen glands

hives

skin redness, peeling or blistering

difficulty breathing or swallowing

swelling of the eyes, face, throat, tongue, or lips

unusual bleeding or bruising

watery or bloody stools, stomach cramps, or fever during treatment or for up to two or more months after stopping treatment 

a return of fever, sore throat, chills, or other signs of infection

joint pain

chest pain

discoloration of permanent (adult) teeth
Doxycycline may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.
If you experience a serious side effect, you or your doctor may send a report to the Food and Drug Administration's (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/Safety/MedWatch) or by phone (1-800-332-1088).

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from light and excess heat and moisture (not in the bathroom).
It is important to keep all medication out of sight and reach of children as many containers (such as weekly pill minders and those for eye drops, creams, patches, and inhalers) are not child-resistant and young children can open them easily. To protect young children from poisoning, always lock safety caps and immediately place the medication in a safe location – one that is up and away and out of their sight and reach. http://www.upandaway.org
Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them.  However, you should not flush this medication down the toilet. Instead, the best way to dispose of your medication is through a medicine take-back program. Talk to your pharmacist or contact your local garbage/recycling department to learn about take-back programs in your community.  See the FDA's Safe Disposal of Medicines website (http://goo.gl/c4Rm4p) for more information if you do not have access to a take-back program.

Keep all appointments with your doctor and laboratory. Your doctor will want to check your response to doxycycline.
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking doxycycline.
Do not let anyone else take your medication. Your prescription is probably not refillable. If you still have symptoms of infection after you finish the doxycycline, call your doctor.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
¶ This branded product is no longer on the market. Generic alternatives may be available.