Cafergot (Caffeine / Ergotamine Tartrate)
Caffeine / Ergotamine Tartrate Information
(er got' a meen) (kaf' een)Do not take ergotamine and caffeine if you are taking antifungals such as itraconazole (Sporanox) and ketoconazole (Nizoral); clarithromycin (Biaxin); erythromycin (E.E.S., E-Mycin, Erythrocin); HIV protease inhibitors such as indinavir (Crixivan), nelfinavir (Viracept), and ritonavir (Norvir); or troleandomycin (TAO).
- Take two tablets at the first sign of a migraine.
- Lie down and relax in a quiet, dark room for at least 2 hours.
- If the headache pain does not stop within 30 minutes, take one or two more tablets.
- Take one or two tablets every 30 minutes until the headache pain stops or you have taken six tablets.
- If the headache pain continues after you have taken six tablets, call your doctor. Do not take more than six tablets for one headache unless your doctor specifically tells you to do so.
- Do not take more than six tablets in 24 hours or 10 tablets in 1 week. If you need more, call your doctor.
- If the suppository feels soft, place it in ice cold water (before removing foil wrapper) until it hardens.
- Remove the wrapper and dip the tip of the suppository in water.
- Lie down on your left side and raise your right knee to your chest. (A left-handed person should lie on the right side and raise the left knee.)
- Using your finger, insert the suppository into the rectum, about 1/2 to 1 inch (1.25 to 2.5 centimeters) in children and 1 inch (2.5 centimeters) in adults. Hold it in place for a few moments.
- Wash your hands thoroughly; then lie down and relax in a dark, quiet room for at least 2 hours.
- If the headache pain does not stop within 1 hour, insert another suppository.
- If the headache pain continues after you have inserted two suppositories, call your doctor. Do not use more than two suppositories for one headache unless your doctor specifically tells you to do so.
- Do not use more than five suppositories in 1 week. If you need more, call your doctor.
Before taking ergotamine and caffeine,
- tell your doctor and pharmacist if you are allergic to ergotamine, caffeine, or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking. Be sure to mention the medications listed in the IMPORTANT WARNING section and any of the following: clotrimazole, fluconazole (Diflucan), fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), medications for asthma and colds, metronidazole (Flagyl), nefazodone (Serzone), propranolol (Inderal), saquinavir (Invirase, Fortovase), and zileuton (Zyflo). Your doctor may need to change the doses of your medications or monitor you carefully for side effects.
- tell your doctor if you have or have ever had high blood pressure; problems with circulation; coronary artery disease; a severe blood infection; or kidney or liver disease.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking ergotamine and caffeine, call your doctor immediately. Ergotamine and caffeine may harm the fetus.
- leg weakness
- chest pain
- rapid heartbeat
- slow heartbeat
- muscle pain in the legs or arms
- blue hands and feet
- pain, burning, or tingling in the fingers and toes