Tigan (Trimethobenzamide Hydrochloride)
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Trimethobenzamide Hydrochloride Information
(trye meth oh ben' za mide)In April 2007, the Food and Drug Administration (FDA) announced that suppositories containing trimethobenzamide may no longer be marketed in the United States. The FDA made this decision because trimethobenzamide suppositories have not been shown to work to treat nausea and vomiting. If you are currently using trimethobenzamide suppositories, you should call your doctor or other healthcare professional to talk about switching to another treatment.
Before taking trimethobenzamide,
- tell your doctor and pharmacist if you are allergic to trimethobenzamide or any other medications.
- tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements and herbal products you are taking or plan to take. Be sure to mention any of the following: antidepressants; antihistamines; barbiturates such as phenobarbital (Luminal); belladonna alkaloids (Donnatal); medications for anxiety, mental illness, pain and seizures; other medications for nausea and vomiting; sedatives; sleeping pills; and tranquilizers. Your doctor may need to change the doses of your medications or monitor you more carefully for side effects.
- tell your doctor if you have Reye's Syndrome (a condition affecting the brain and liver that can happen after a viral illness), encephalitis (inflammation of the brain), or a high fever, or if you have or have ever had liver disease. If you will be giving trimethobenzamide to a child, also tell the child's doctor if the child has any of the following symptoms before he or she receives the medication: vomiting, listlessness, drowsiness, confusion, aggression, seizures, yellowing of the skin or eyes, weakness, or flu-like symptoms. Also tell the child's doctor if the child has not been drinking normally, has had excessive vomiting or diarrhea, or appears dehydrated.
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking trimethobenzamide, call your doctor.
- if you are having surgery, including dental surgery, tell the doctor or dentist that you are taking trimethobenzamide.
- you should know that this medication may make you drowsy. Do not drive a car or operate machinery until you know how this medication affects you.
- ask your doctor about the safe use of alcoholic beverages while you are taking trimethobenzamide. Alcohol can make the side effects from trimethobenzamide worse.
- backward arching of the head, neck, and back
- muscle cramps
- uncontrollable shaking of a part of the body
- slow, jerking movements
- shuffling walk
- slow speech
- blurred vision
- yellowing of the skin or eyes
- coma (loss of consciousness for a period of time)